Role of Neisseria meningitidis luxS in cell-to-cell signaling and bacteremic infection.
نویسندگان
چکیده
Numerous pathogenic bacteria contain luxS, which is required for autoinducer-2 production. Here, we demonstrate that Neisseria meningitidis contains a functional copy of luxS that is necessary for full meningococcal virulence; strains with a luxS deletion are defective for bacteremia, a prerequisite of meningococcal pathogenesis.
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عنوان ژورنال:
- Infection and immunity
دوره 70 4 شماره
صفحات -
تاریخ انتشار 2002